艾灸对实验性RA家兔IL-10、IL-17、OPN的影响          下载免费PDF全文

任继刚  雷枭  王大雪 《应用海洋学学报》2019,35(9):140-141

目的：观察艾灸对实验性类风湿性关节炎（RA）家兔外周血中白细胞介素（IL）-10、IL-17及骨桥蛋白（OPN）表达的影响，并探索艾灸治疗RA的抗炎机制。方法：选取日本大耳白兔30只，将其随机分为空白组、模型组、治疗组，每组各10只，采用福氏完全佐剂法制备实验性RA模型。在造模后第7天，治疗组采用悬灸肾俞、足三里穴疗法，每穴各灸5壮，　1次/d，以6d为1个疗程，共干预3个疗程。检测各组血清中IL-10、IL-17及OPN的含量。结果：IL-10、IL-17、OPN模型组与空白组比较，治疗组与模型组比较，差异均有统计学意义（P<0.01）。结论：艾灸治疗对实验性RA家兔有显著的抗炎作用，可有效降低血清IL-17及OPN含量，上调IL-10的表达，其抗炎的作用机制可能是通过调节OPN的表达，进而调节Th17/Treg而实现的。  相似文献   

A comparison of the effectiveness of the roots of two grass species in reducing soil erosion on alluvial fans in south-east China     

Fangshi Jiang  Kaiwen He  Jiahui Lin  Hui Li  Zhenzhi Zhan  Jinshi Lin  Hongli Ge  Ming Kuang Wang  Yanhe Huang 《水文研究》2020,34(1):96-110

The effects of root systems on soil detachment by overland flow are closely related to vegetation types. The objective of this study was to quantify the effects of two gramineous roots (Paspalum mandiocanum with shallow roots and Pennisetum giganteum with deep roots) on soil detachment capacity, rill erodibility, and critical shear stress on alluvial fans of benggang in south-east China. A 4-m-long and 0.12-m-wide flume was used. Slope steepness ranged from 9% to 27%, and unit flow discharge ranged from 1.39 × 10⁻³ to 4.19 × 10⁻³ m² s⁻¹. The mean detachment capacities of P. mandiocanum and P. giganteum lands were 18% and 38% lower than that of bare land, respectively, and the effects of root on reducing soil detachment were mainly reflected in the 0- to 5-cm soil layer. The most important factors in characterizing soil detachment capacity were root length density and soil cohesion, and soil detachment capacity of the two grass lands could be estimated using flow shear stress, soil cohesion, and root length density (NSE = 0.90). With the increase in soil depth, rill erodibility increased, whereas shear stress decreased. The mean rill erodibilities of P. mandiocanum and P. giganteum lands were 81% and 61% as much as that of bare land, respectively. Additionally, rill erodibilities of the two grass lands could be estimated as an exponential function by root length density and soil cohesion (NSE = 0.88). The mean critical shear stress of P. mandiocanum and P. giganteum lands was 1.29 and 1.39 times that of bare land, respectively, and it could be estimated with a linear function by root length density (NSE = 0.76). This study demonstrated that planting of the two grasses P. mandiocanum and P. giganteum could effectively reduce soil detachment and enhance soil resistance to erosion on alluvial fans, with the deep roots of P. giganteum being more effective than the shallow roots of P. mandiocanum. The results are helpful for understanding the influencing mechanism of root systems on soil detachment process.  相似文献   

Variations in glacier volume and snow cover and their impact on lake storage in the Paiku Co Basin,in the Central Himalayas     

Xingxing Zhang  Rui Wang  Zhijun Yao  Zhaofei Liu 《水文研究》2020,34(8):1920-1933

Glaciers and snow cover are important constituents of the surface of the Tibetan Plateau. The responses of these phenomena to global environmental changes are sensitive, rapid and intensive due to the high altitudes and arid cold climate of the Tibetan Plateau. Based on multisource remote sensing data, including Landsat images, MOD10A2 snow product, ICESat, Cryosat-2 altimetry data and long-term ground climate observations, we analysed the dynamic changes of glaciers, snow melting and lake in the Paiku Co basin using extraction methods for glaciers and lake, the degree-day model and the ice and lake volume method. The interaction among the climate, ice-snow and the hydrological elements in Paiku Co is revealed. From 2000 to 2018, the basin tended to be drier, and rainfall decreased at a rate of −3.07 mm/a. The seasonal temperature difference in the basin increased, the maximum temperature increased at a rate of 0.02°C/a and the minimum temperature decreased at a rate of −0.06°C/a, which accelerated the melting from glaciers and snow at rates of 0.55 × 10⁷ m³/a and 0.29 × 10⁷ m³/a, respectively. The rate of contribution to the lake from rainfall, snow and glacier melted water was 55.6, 27.7 and 16.7%, respectively. In the past 18 years, the warmer and drier climate has caused the lake to shrink. The water level of the lake continued to decline at a rate of −0.02 m/a, and the lake water volume decreased by 4.85 × 10⁸ m³ at a rate of −0.27 × 10⁸ m³/a from 2000 to 2018. This evaluation is important for understanding how the snow and ice melting in the central Himalayas affect the regional water cycle.  相似文献   

A comparison of methods to estimate groundwater recharge from bare soil based on data observed by a large-scale lysimeter     

Zaiyong Zhang  Wenke Wang  Chengcheng Gong  Ming Zhang 《水文研究》2020,34(13):2987-2999

Effectively estimating groundwater recharge is critical to manage water resources, especially in arid and semi-arid regions as impacted by intensive human activities and climate changes. Rare insights have been gained into groundwater recharge since direct observation is hard to carry out. Although several methods are currently available to estimate groundwater recharge, the estimated results may cover noticeable bias. The behaviours of different methods based on different conceptual frameworks and exhibiting different levels of complexity should be examined to estimate actual groundwater recharge. This study aims to assess the performance of four common methods to estimate groundwater recharge. For this end, large-scale lysimeters equipped with soil water content sensors and water table sensors were set up at a research site established in Guanzhong Basin of China. The data achieved by 1-year observation were employed to compare four estimation methods. As revealed from the results, the following findings are drawn. (a) Groundwater level fluctuation (GLF) method is simple, whereas its accuracy is determined by specific yield, and adopting a water balance method to estimate specific yield can considerably enhance the accuracy of GLF. (b) The calibrated numerical model can obtain the optimal result compared with the other methods, whereas long-term observation data are required for parameter calibration. (c) In the water balance method, the maximum entropy production (MEP) model and a practical method (estimating evaporation between two rainfall events) were used to calculate evaporation. As indicated by the results, water balance method combined with MEP is capable of obtaining more reliable results of groundwater recharge compared with the practical method. (d) With an analytical model based on linearized Richards' equation, accurate results can be achieved. What is more, the analytical model only needs the measurement of soil moisture near the surface. The limitation of this method is that it is difficult to determine the maximal water flux. The mentioned findings are of critical implications to the management and sustainable development of groundwater.  相似文献   

顾及地形起伏的无人机影像覆盖分析方法     

张衡  李骁  叶朋飞 《测绘通报》2020,(1):102-106

使用无人机实施测绘航空摄影时，由于无人机相对航高较低，地面起伏会对无人机影像的分辨率、覆盖范围、重叠度造成较大的影响，影像成果会出现分辨率不足、重叠度不够、覆盖漏洞等缺陷。针对这一情况，本文提出了一种利用数字微分正解法的计算方法，借助DEM准确计算每张影像的覆盖范围，并使用FME软件高效生成全部影像的覆盖范围。经过实际使用，验证了该方法可以在航线设计阶段准确预测并分析全部影像的覆盖范围、重叠度，因此可及时发现设计问题并调整航线。该方法可以有效减少因地形起伏造成的影像覆盖缺陷，减少返工现象，从整体上提高了作业效率。  相似文献   

资源三号和天绘一号卫星影像无控联合平差精度分析     

郑义  张宏伟  杜晓  张俊辉  周琦  林尚纬  陈利军 《测绘通报》2020,(7):10

近年来国产卫星传感器类型日益丰富，使用自主可控的国产卫星影像进行生产和研究的需求越来越大，多源国产卫星影像联合平差的精度分析显得尤为重要。本文针对在立体测图生产中，资源三号卫星影像在时相较旧、噪声较大、云覆盖和摄影漏洞等特殊困难的条件下，利用天绘一号卫星影像进行补漏生产的情况，最终分析并验证了两者无控联合平差的可行性和成果精度。  相似文献   

A probabilistic framework for improving reverse geocoding output     

Zhengcong Yin  Daniel W. Goldberg  Tracy A. Hammond  Chong Zhang  Andong Ma  Xiao Li 《Transactions in GIS》2020,24(3):656-680

Reverse geocoding, which transforms machine‐readable GPS coordinates into human‐readable location information, is widely used in a variety of location‐based services and analysis. The output quality of reverse geocoding is critical because it can greatly impact these services provided to end‐users. We argue that the output of reverse geocoding should be spatially close to and topologically correct with respect to the input coordinates, contain multiple suggestions ranked by a uniform standard, and incorporate GPS uncertainties. However, existing reverse geocoding systems often fail to fulfill these aims. To further improve the reverse geocoding process, we propose a probabilistic framework that includes: (1) a new workflow that can adapt all existing address models and unitizes distance and topology relations among retrieved reference data for candidate selections; (2) an advanced scoring mechanism that quantifies characteristics of the entire workflow and orders candidates according to their likelihood of being the best candidate; and (3) a novel algorithm that derives statistical surfaces for input GPS uncertainties and propagates such uncertainties into final output lists. The efficiency of the proposed approaches is demonstrated through comparisons to the four commercial reverse geocoding systems and through human judgments. We envision that more advanced reverse geocoding output ranking algorithms specific to different application scenarios can be built upon this work.  相似文献   

Quantifying suitable dynamic water levels in marsh wetlands based on hydrodynamic modelling     

Peng Hu  Zefan Yang  Qiande Zhu  Weize Wang  Qin Yang 《水文研究》2021,35(2):e14054

The water level of marsh wetlands is a dominant force controlling the wetland ecosystem function, especially for aquatic habitat. For different species, water level requirements vary in time and space, and therefore ensuring suitable water levels in different periods is crucial for the maintenance of biodiversity in marsh wetlands. Based on hydrodynamic modelling and habitat suitability assessment, we determined suitable dynamic water levels considering aquatic habitat service at different periods in marsh wetlands. The two-dimensional hydrodynamic model was used to simulate the temporal and spatial variation of water level. The habitat suitability for target species at various water levels was evaluated to obtain the fitting curves between Weighted Usable Area (WUA) and water levels. And then suitable water levels throughout the year were proposed according to the fitting curves. Using the Zhalong Wetland (located in northeastern China) as a case study, we confirmed that the proposed MIKE 21 model can successfully be used to simulate the water level process in the wetland. Suitable water levels were identified as being from 143.9–144.2 m for April to May, 144.1–144.3 m for June to September, and 144.3–144.4 m for October to November (before the freezing season). Furthermore, proposed water diversion schemes have been identified which can effectively sustain the proposed dynamic water levels. This study is expected to provide appropriate guidance for the determination of environmental flows and water management strategies in marsh wetlands.  相似文献   

Effects of rainfall intensity and compaction on water transport from opencast coal mine soils: An experimental study     

Fengjiao Wang  Jinman Wang 《水文研究》2020,34(2):258-269

The use of heavy machinery during opencast coal mining can result in soil compaction. Severe soil compaction has a negative impact on the transport of water and gas in the soil. In addition, rainfall intensity has traditionally been related to soil surface sealing affecting water transport. To assess the effects of rainfall intensity and compaction on water infiltration and surface runoff in an opencast coal mining area, the disturbed soils from the Antaibao opencast mine in Shanxi Province, China, were collected. Four soil columns with different bulk densities (i.e., 1.4 g cm^-3, 1.5 g cm^-3, 1.6 g cm^-3, and 1.7 g cm^-3) were designed, and each column received water five times at rainfall intensities of 23.12, 28.91, 38.54, 57.81, and 115.62 mm hr^-1. The total volume of runoff, the time to start runoff, and the volumetric water contents at the depths of 5 cm, 15 cm, 25 cm, 35 cm, 45 cm, 55 cm, and 65 cm were measured. Under the same soil bulk density, high rainfall intensity reduced infiltration, increased surface runoff, and decreased the magnitude of change in the volumetric water contents at different depths. Under the same rainfall intensity, the soil column with a high bulk density showed relatively low water infiltration. Treatments 3 (1.6 g cm^-3) and 4 (1.7 g cm^-3) had very small changes in volumetric water contents of the profiles even under a lower rainfall intensity. Severe soil compaction was highly prone to surface runoff after rainfall. Engineering and revegetation measures are available to improve compacted soil quality in dumps. Our results provide a theoretical basis for the management of land reclamation in opencast coal mine areas.  相似文献   

路网约束条件下热力规则设计与试验     

杜晓  周玉秀  周琦  郑义  张俊辉  林尚纬  陈利军 《测绘通报》2020,(7):18-21

热力图是一种能直观准确展示空间观测值的有效工具，在多个领域具有广泛应用。本文在分析设定不同道路层权重、道路技术等级分类的基础上，以反距离权重、直方图均衡化、密度补偿、参数多次迭代等方法，研究构建了以热力方式展示道路网分布及发达程度的相关规则体系。热力规则通过道路赋权、路线曲面化、密度协调、图面综合等多套规则的有机结合，实现了道路网总体发达水平信息的提取与展示，并以全球地理信息资源建设项目路网成果中的亚洲和非洲部分国家数据为例，进行了信息提取与热力分布试验。  相似文献